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KMID : 0604020150300020082
Korean Journal of Critical Care Medicine
2015 Volume.30 No. 2 p.82 ~ p.88
Pharmacotherapeutic Problems and Pharmacist Interventions in a Medical Intensive Care Unit
Park Tae-Yun

Lee Sang-Min
Kim Sung-Eun
Yoo Ga-Eun
Choi Go-Wun
Jo Yun-Hee
Cho Yoon-Sook
Hahn Hyeon-Joo
Lee Jin-Woo
Kim A-Jeong
Abstract
Background: Interest in pharmacist participation in the multidisciplinary intensive care team is increasing. However, studies examiningpharmacist interventions in the medical intensive care unit (MICU) are limited in Korea. The aim of this study was to describe thecurrent status of pharmacist interventions and to identify common pharmacologic problems requiring pharmacist intervention in theMICU.

Methods: Between September 2013 and August 2014, a retrospective, observational study was conducted in the 22-bed MICU at auniversity hospital. Data were obtained from two trained pharmacists who participated in MICU rounds three times a week. In additionto patient characteristics, data on the cause, type, related drug, and acceptance rate of interventions were collected.

Results: In 340 patients, a total of 1211 pharmacologic interventions were performed. The majority of pharmacologic interventionswere suggested by pharmacists at multidisciplinary rounds in the MICU. The most common pharmacologic interventions were adjustmentof dosage and administration (n = 328, 26.0%), followed by parenteral/enteral nutritional support (n = 228, 18.1%), the provisionof drug information (n = 228, 18.1%), and advice regarding pharmacokinetics (n = 118, 9.3%). Antimicrobial agents (n = 516, 42.6%)were the most frequent type of drug associated with pharmacist interventions. The acceptance rate of interventions was 84.1% withmost accepted by physicians within 24 hours (n = 602, 92.8%).

Conclusions: Medication and nutritional problems are frequently encountered pharmacotherapeutic problems in the MICU. Pharmacistinterventions play an important role in the management of these problems.
KEYWORD
intensive care unit, intervention, pharmacist
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